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Updated: May 13, 2026
In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears
Published on: February 21, 2018
[Quantitative analysis of psychiatric disorders in patients with intractable Meniere's disease]
Feng Zhai1, Manyun Yan, Guoming Zhang
1Department of Otology and Skull Base Surgery, Eye Ear Nose and Throat Hospital, Fudan University,Shanghai, 200031, China.
Objective:
To investigate the correlation between psychological disorder and vestibular dysfunction in patients suffering from peripheral vertigo.
Method:
Retrospective review of 17 peripheral vertiginous patients with intractable Meniere's disease recruited from the EENT hospital whom underwent intratympanic gentamicin injection. Hospital anxiety and depression scale, self-rating anxiety scale, self-rating depression scale, symptom checklist-90 were used in this study. Pre- and postoperative scores where compared.
Result:
The vertigo control rate of 17 patients reached 88%, with hearing impairment noted only in 17.6% of the patients. 33.3% of the preoperative tinnitus patients and 76.9% of the preoperative aural fullness patients had their symptoms relieved respectively. The outcomes of hospital anxiety and depression scale, self-rating anxiety scale, self-rating depression scale, symptom checklist-90 are significantly greater in vertiginous group than that in normal controls (P < 0. 01). The preoperative scores of these 4 questionnaires are greater than the postoperative scores in vertiginous patients (P < 0.05). No significant difference was noted between male and female participants in all the questionnaires used (P > 0.05).
Conclusion:
Significant differences were noted between peripheral vertiginous patients and normal controls in psychiatric questionnaires, suggesting that psychological dysfunction may contribute to the vertigo attack.
