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Updated: May 13, 2026
Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Sinonasal inverted papilloma: 43 cases]
Mohamed Ben Amor1, Nadia Romdhane, Zoubaida Khalifa
1Hôpital Habib Thameur Tunis, service ORL et CCF, 8, rue Ali-Ben-Ayed, Montfleury 1008, Tunisie. medbenamor76@yahoo.fr
Purpose:
Inverted papilloma (IP) is a common epithelial tumor arising from the nasal vault. The aim of our study was to evaluate the advantages, the results and the limits in the treatment of this tumor.
Patients And Method:
Retrospective study of 43 patients over the period 1989-2009.
Results:
The mean age was 53.3 years. We found a maxillary sinus extension in 40 cases and ethmoidal extension in 27 cases. Twenty-nine patients were treated through an endoscopic endonasal approach. A vestibular approach was used in three patients. A paralateral nasal approach was used for 12 cases. We observed a recurrence in 9.3% of the all cases.
Conclusion:
The treatment of IP is surgical. Their high potential of local aggressiveness, fear of recurrence and the possibility of the occurrence of a malignancy require radical treatment.
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Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...