Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cortical development dynamics across autism spectrum disorder mouse models.

Nature·2026
Same author

[Patellar fractures : Overview of surgical treatment concepts].

Operative Orthopadie und Traumatologie·2026
Same author

The small distractor-a useful tool for the trauma surgeon.

Operative Orthopadie und Traumatologie·2026
Same author

Multifold increase in spinal inhibitory cell types with emergence of limb movement.

Cell reports·2026
Same author

[Biphasic plate-Controlled instability in fracture healing].

Unfallchirurgie (Heidelberg, Germany)·2025
Same author

[Lesion of the sciatic nerve after antegrade intramedullary nailing of proximal femoral fractures].

Unfallchirurgie (Heidelberg, Germany)·2025
Same journal

[Multimodal Cardiac Imaging: New Developments for Clinical Practice].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Coronary angiography: From cardiac catheterization to advanced interventional cardiovascular imaging].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Athlete's heart: role of cardiac imaging in the prevention of sudden cardiac death].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Multimodal imaging in cardiac amyloidosis and cardiac sarcoidosis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Inflammatory Heart Disease: The Role of Multimodality Cardiac Imaging in Myocarditis and Pericarditis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

State-of-the-Art Cardiac Imaging

Therapeutische Umschau. Revue therapeutique·2026
See all related articles

Related Experiment Video

Updated: May 13, 2026

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
02:09

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions

Published on: December 20, 2024

[Traumatic splenic injury].

Thomas S Müller1, Christoph Sommer

  • 1Departement Chirurgie, Kantonsspital Graubünden, Chur. thomas.mueller@ksgr.ch

Therapeutische Umschau. Revue Therapeutique
|March 5, 2013
PubMed
Summary
This summary is machine-generated.

Hemodynamically stable patients with blunt splenic injury are now successfully treated non-operatively in 80% of cases. Angiographic embolization further increases non-operative management success rates to nearly 95%.

Related Experiment Videos

Last Updated: May 13, 2026

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
02:09

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions

Published on: December 20, 2024

Area of Science:

  • Trauma surgery
  • Surgical innovation
  • Emergency medicine

Context:

  • The management of splenic injuries has evolved significantly over the past 30 years.
  • Historically, operative intervention was standard for splenic trauma.
  • A paradigm shift has occurred in treating blunt splenic injury in hemodynamically stable patients.

Purpose:

  • To review the current management strategies for blunt splenic injury.
  • To highlight the success of non-operative management (NOM) for hemodynamically stable patients.
  • To discuss the role of angiographic embolization in improving NOM outcomes.

Summary:

  • Immediate operative intervention remains standard for penetrating and hemodynamically unstable splenic injuries.
  • Approximately 80% of hemodynamically stable blunt splenic injury patients can be successfully managed non-operatively.
  • Angiographic embolization, when used selectively, enhances NOM success rates, approaching 95%.

Impact:

  • Non-operative management is now the preferred approach for stable blunt splenic injuries.
  • This shift reduces unnecessary surgeries, associated morbidity, and healthcare costs.
  • Improved outcomes demonstrate the efficacy of modern interventional radiology techniques in trauma care.