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Updated: May 13, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
Esophageal metastasis from papillary thyroid cancer: diagnosis by 131I SPECT/CT
Christian Wisotzki1, Michael Friese, Jörg Ehresmann
1From the *Department of Nuclear Medicine, University Medical Center Hamburg-Eppendorf; †Institute of Pathology and Neuropathology Asklepios Clinic North Hamburg; and ‡Department of Gastroenterology and Oncology, Asklepios Clinic North Hamburg, Hamburg, Germany.
Abstract:
We report a case of esophageal metastasis from papillary thyroid cancer diagnosed by I SPECT/CT. A 70-year-old man presented with increasing thyroglobulin levels 13 years after thyroidectomy and ablation with I for thyroid cancer. The whole-body radioiodine scan demonstrated marked tracer uptake in the mediastinum, and SPECT/CT could clearly localize the activity to the esophagus. Subsequent surgical resection with histopathologic evaluation revealed an esophageal metastasis from papillary thyroid cancer. I SPECT/CT is a valuable tool for evaluation and precise anatomical localization of the foci of radionuclide activity in thyroid cancer, enabling adequate treatment.
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