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Updated: May 13, 2026
12:28
Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies
Published on: March 12, 2022
Diabetic retinopathy and VEGF
The Open Ophthalmology Journal
|March 6, 2013
Summary
Diabetic retinopathy, a leading cause of blindness, is managed with anti-vascular endothelial growth factor (VEGF) therapies. This review explores VEGF
Area of Science:
- Ophthalmology
- Endocrinology
- Vascular Biology
Background:
- Diabetic retinopathy is a primary cause of vision loss globally.
- Current treatments involve laser photocoagulation, steroids, anti-VEGF agents, and blood sugar control.
- Anti-VEGF therapies offer a safer alternative to laser treatments for diabetic macular edema (DME).
Purpose of the Study:
- To provide comprehensive information on vascular endothelial growth factor (VEGF).
- To elucidate the role of VEGF in diabetic retinopathy pathogenesis.
- To examine antiangiogenic agents' mechanisms in managing diabetic retinopathy.
Main Methods:
- Literature review using Medline (PubMed) database.
- Keywords: "VEGF", "diabetic retinopathy", "diabetes".
- No year limitation for manuscript search.
Main Results:
- VEGF plays a critical role in diabetic retinopathy development.
- Anti-VEGF agents are effective in managing vision-threatening complications like DME.
- Understanding VEGF mechanisms aids in developing targeted therapies.
Conclusions:
- Anti-VEGF therapies are a key component in managing diabetic retinopathy.
- Further research into antiangiogenic agents can improve patient outcomes.
- Multidisciplinary management is crucial for diabetic retinopathy patients.
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