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Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
Published on: February 7, 2018
Acoustically controlled enhancement of molecular sensing to assess oxidative stress in cells
Julien Reboud1, Craig Auchinvole, Christopher D Syme
1Division of Biomedical Engineering, University of Glasgow, Oakfield Avenue, Glasgow, G12 8LT, UK.
Chemical Communications (Cambridge, England)
|March 6, 2013
Abstract:
We demonstrate a microfluidic platform for the controlled aggregation of colloidal silver nanoparticles using surface acoustic waves (SAWs), enabling surface enhanced Raman scattering (SERS) analysis of oxidative damage in cells. We show that by varying the frequency and the power of the acoustic energy, it is possible to modulate the aggregation of the colloid within the sample and hence to optimise the SERS analysis.
