Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems.

James E DiCarlo1, Julie E Norville, Prashant Mali

  • 1Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.

Summary

This study demonstrates the successful application of the CRISPR-Cas9 system for genome engineering in yeast. The system enables precise DNA modifications, significantly enhancing homologous recombination for gene editing applications.

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