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Published on: June 18, 2021
Seizures and intracranial hemorrhage
Karen L Wilson1, James M Alexander
1Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. KarenL.Wilson@UTSouthwestern.edu
Obstetricians may encounter seizures and intracranial hemorrhage during pregnancy. This review covers their causes, treatments, and overlap with preeclampsia/eclampsia, focusing on management challenges.
Area of Science:
- Obstetrics and Gynecology
- Neurology
- Critical Care Medicine
Background:
- Seizures and intracranial hemorrhage are critical neurological emergencies that can occur during pregnancy.
- These conditions pose significant risks to both the pregnant individual and the fetus.
- Overlap with hypertensive disorders like preeclampsia and eclampsia complicates management.
Purpose of the Study:
- To review the etiology, treatment, and medical management of seizures in pregnancy.
- To review the etiology, treatment, and medical management of intracranial hemorrhage in pregnancy.
- To explore the intersection of these conditions with preeclampsia and eclampsia and highlight obstetric management challenges.
Main Methods:
- Literature review of causes, diagnostic approaches, and therapeutic strategies for seizures and intracranial hemorrhage in pregnancy.
- Analysis of clinical scenarios and management guidelines.
- Discussion of challenging cases from an obstetrician's viewpoint.
Main Results:
- Identified common and rare causes of seizures and intracranial hemorrhage in pregnant individuals.
- Outlined current treatment protocols, including anticonvulsant therapy and surgical interventions where applicable.
- Emphasized the diagnostic and therapeutic complexities arising from concurrent preeclampsia/eclampsia.
Conclusions:
- Effective management requires a multidisciplinary approach, integrating obstetrics, neurology, and critical care.
- Early recognition and prompt intervention are crucial for improving maternal and fetal outcomes.
- Further research into optimal management strategies for these overlapping conditions is warranted.
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Increased Intracranial Pressure l: Introduction

