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Related Concept Videos

Histology of the Uterus01:19

Histology of the Uterus

The uterine wall consists of three histological layers: the perimetrium, myometrium, and endometrium. The outermost perimetrium is a thin, serous membrane connected with the broad ligament on the sides, which helps anchor the uterus in the pelvic cavity. The thickest layer, myometrium, is mainly made up of smooth muscle tissue bundles. Its contractions are vital in facilitating the expulsion of the uterine lining, fetus, and placenta during menstruation and childbirth.
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After a large-single-celled zygote is produced via fertilization, the process of cleavage occurs while zygotes travel through the uterine tube. Cleavage is a mitotic cell division that does not result in growth. With each round of successive cell division, daughter cells get increasingly smaller.

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Related Experiment Video

Updated: May 13, 2026

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
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Published on: June 27, 2025

Placenta accreta, increta, and percreta.

Alison C Wortman1, James M Alexander

  • 1Department of Maternal Fetal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Alison.Wortman@UTSouthwestern.edu

Obstetrics and Gynecology Clinics of North America
|March 8, 2013
PubMed
Summary

Placenta accreta, abnormal placental adherence, is rising with cesarean deliveries. Prenatal diagnosis via ultrasound and risk factor identification aid in planning deliveries for better maternal outcomes.

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Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine

Background:

  • Placenta accreta involves abnormal placental adherence to the uterine wall, posing risks of maternal morbidity and mortality.
  • The incidence of placenta accreta has significantly increased, correlating with rising cesarean delivery rates.
  • Early identification and management are crucial for improving patient outcomes.

Purpose of the Study:

  • To highlight the increasing incidence of placenta accreta.
  • To emphasize the role of prenatal diagnosis in managing this condition.
  • To recommend strategies for improved delivery planning and patient care.

Main Methods:

  • Review of existing literature and clinical data on placenta accreta.
  • Analysis of the correlation between cesarean delivery rates and placenta accreta incidence.
  • Identification of key risk factors and diagnostic tools, such as ultrasound.

Main Results:

  • Placenta accreta incidence has risen 13-fold since the early 1900s.
  • A direct correlation exists between increasing cesarean delivery rates and placenta accreta.
  • Prenatal diagnosis using ultrasound, alongside identifying risk factors like placenta previa and prior cesarean delivery, is effective.

Conclusions:

  • Prenatal diagnosis of placenta accreta is vital for effective delivery planning.
  • Recognizing risk factors such as placenta previa and previous cesarean deliveries improves management.
  • Referral to tertiary care centers and multidisciplinary teams are recommended for optimal care.