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Updated: May 13, 2026
A Syngeneic Orthotopic Osteosarcoma Sprague Dawley Rat Model with Amputation to Control Metastasis Rate
Published on: May 3, 2021
[Primary cutaneous osteosarcoma]
A Ben M'na1, I Chelly, A Souissi
1Service d'anatomopathologie, hôpital La Rabta, Jabbari, Bab Saadoun, 1007 Tunis, Tunisie. amirabenmna@gmail.com
Background:
Osteosarcoma is a malignant tumor of mesenchymatous origin that chiefly affects the metaphysis of long bones. The extraskeletal form of the disease is rare, and even rarer is a cutaneous site, whether metastatic or primary. Herein, we report a new case of primary cutaneous osteosarcoma.
Patients And Methods:
A 54-year-old woman presented a hard subcutaneous nodular tumor on her left arm noted 1 year earlier. The diagnosis of cutaneous osteosarcoma was made on the basis of histological analysis of the lesion, which showed a sarcomatous dermal-hypodermal proliferation secreting osteoid. Clinical and radiological staging ruled out any extra-cutaneous spread, particularly to bone, thus confirming the primary cutaneous nature of the osteosarcoma.
Discussion:
Primary cutaneous osteosarcoma is a rare tumor, diagnosis of which is normally based on histopathological features.
