Related Experiment Video
Updated: May 13, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
Osteoporosis: genetic determinants and relationship with cardiovascular disease
Małgorzata Sobieszczańska1, Jakub Jonkisz, Mateusz Tabin
1Department of Pathophysiology, Wroclaw Medical University, Wroclaw, Poland. malsobie@poczta.onet.pl
Abstract:
Osteoporosis has become one of the major public health problems, affecting about two hundred million people worldwide, including one third of all postmenopausal women. The paper presents a review of the current literature concerning the pathophysiology and the most common genetic and environmental determinants that account for the individual predisposition to age-related osteoporosis. Particular emphasis is placed on the specific linkage between the causative factors of osteoporosis and atherosclerotic cardiovascular disease.
Related Concept Videos
Coronary Artery Disease I: Introduction
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Coronary Artery Disease II: Pathophysiology
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu
Regulation of the Cardiovascular System
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
Principles of Pharmacogenetics: Types of Genetic Variants