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Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...
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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
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Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...

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Sino-Canadian collaborations in stem cell research: a scientometric analysis.

Sarah E Ali-Khan1, Monali Ray, Dominique S McMahon

  • 1Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

Plos One
|March 8, 2013
PubMed
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International collaboration in stem cell research is crucial. China-Canada stem cell research collaboration is increasing and enhances scientific impact, despite China

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Area of Science:

  • Stem cell research
  • International scientific collaboration
  • Scientometrics

Background:

  • Stem cell research is vital but faces knowledge and capacity disparities between nations.
  • China is a rising global leader in stem cell research.
  • Limited understanding exists regarding international collaboration patterns, especially between China and developed economies.

Purpose of the Study:

  • To conduct a scientometric analysis of stem cell research collaboration between China and Canada.
  • To contextualize China-Canada collaboration within the global landscape of stem cell research.
  • To examine the characteristics, impact, and trends of this specific international collaboration.

Main Methods:

  • Analysis of stem cell research papers published between 2006 and 2010 sourced from the Scopus database.
  • Utilized co-authored publications as a metric for international collaboration (IC).
  • Examined IC levels, institutional partnerships, research focus, funding, and scientific impact.

Main Results:

  • The global stem cell research field expanded by 48% from 2006-2010, with China ranking second globally.
  • China exhibited the lowest IC rate among examined countries, while Canada had one of the highest.
  • China-Canada collaboration more than doubled between 2006-2010 and significantly enhanced research impact compared to China-only publications.

Conclusions:

  • International collaboration enhances the impact of stem cell research in China and globally.
  • China's rise in stem cell research is largely driven by domestic publications, but IC is increasingly important.
  • This study provides a baseline for future research into the dynamics of international stem cell research collaboration.