Related Experiment Video
Updated: May 13, 2026

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
Published on: August 21, 2017
Early onset optic neuritis following measles-rubella vaccination
Siamak Moradian1, Hamid Ahmadieh
1Ophthalmic Research Center, Labbafinejad Medical Center, Shahid Beheshti University MC, Tehran, Iran.
Purpose:
To report two cases of optic neuritis with onset less than 24 hours following measles-rubella (MR) vaccination.
Case Report:
Two teenage patients developed acute optic neuritis 6 to 7 hours after MR booster vaccination. The first patient demonstrated bilateral papillitis and severe visual loss but improved significantly with pulse intravenous steroid therapy with methylprednisolone 500 mg/day. The second patient had unilateral retrobulbar optic neuritis and demonstrated excellent visual recovery without intervention.
Conclusion:
Acute optic neuritis is a rare complication of MR vaccination and may occur early after immunization.
Insights
Measles-rubella (MR) vaccination can rarely cause acute optic neuritis, an eye inflammation. This condition may manifest rapidly, within hours of receiving the MR vaccine.
Area of Science:
- Ophthalmology
- Neurology
- Immunology
Background:
- Optic neuritis is an inflammatory condition affecting the optic nerve.
- Vaccinations are crucial for public health but can rarely have adverse effects.
- Measles-rubella (MR) vaccination is widely administered for infectious disease prevention.
More Related Videos
07:50A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
12:23Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
Related Concept Videos
Encephalitis l: Introduction
Encephalitis ll: Pathophysiology
Multiple Sclerosis l: Introduction
Arboviral Encephalitis
Viral Meningitis
Cytomegalovirus Disease