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Published on: August 16, 2024
A rare ovarian tumor, leydig stromal cell tumor, presenting with virilization: a case report
Soheila Aminimoghaddam1, Atefeh-Sadat Ebrahimi, Forough Hashemi
1Gynecologist-Oncologist, Assistant Professor of Medicine, Department of gynecology, Firoozgar Hospital, Tehran University of Medical Sciences, Tehran, Iran. dr.aminimoghaddam@yahoo.com.
Abstract:
Leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. They produce testosterone leading to hyperandrogenism. We present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra Sonography, and a rise of total and free serum testosterone. An ovarian source of androgen was suspected and a surgery performed. A diagnosis of leydig-stromal cell tumor was confirmed. Our report is a reminder that although idiopathic hirsutism and other benign androgen excess disorder like Polycystic Ovarian Syndrome (PCOs) are common, ovarian mass should be considered in differential diagnosis.
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