Related Experiment Video
Updated: May 13, 2026
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
A novel combined surgical approach to head and neck dermatofibrosarcoma protuberans
Tommaso Agostini1, Mario Dini, Alessandro Quattrini Li
1Department of Plastic and Reconstructive, CTO-AOUC, University of Florence, Largo Palagi 1, 50134, Italy; Department of Maxillo-Facial Surgery, CTO-AOUC, University of Florence, Italy.
Introduction:
The surgical management of dermatofibrosarcoma protuberans has historically been a challenge, particularly in the head and neck and other aesthetic areas. The current priority is to achieve local oncologic control and a good reconstructive outcome. Here, we present our experience using a novel combined approach with a dermal regenerative template, sub-atmospheric pressure and skin graft.
Materials And Methods:
Five patients presenting at the Department of Plastic and Reconstructive Surgery of the University of Florence between January 2010 and October 2011 were included in the study following Institutional Review Board approval. All patients underwent a wide local excision of dermatofibrosarcoma protuberans affecting the head and neck.
Results:
The combined approach using the negative-pressure device, a dermal regenerative template and skin grafting proved effective in the management of this type of sarcoma with a good aesthetic and functional outcome, particularly on the neck or the supraclavicular region.
Conclusion:
Although the present multi-step technique requires patient compliance, it results in good local oncologic control of the resection margins. It is possible to perform a wider excision in the event of positive margins without interfering with the last reconstructive outcome.
