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Insulin therapies: Current and future trends at dawn
1Subhashini Yaturu, Endocrinology Section, Stratton VA Medical Center, Albany, NY 12208, United States.
World Journal of Diabetes
|March 16, 2013
Summary
Current insulin delivery methods for diabetes are invasive. Research is exploring non-invasive alternatives like transdermal, buccal, oral, and pulmonary routes for improved patient comfort and adherence.
Area of Science:
- Endocrinology
- Biomedical Engineering
- Pharmaceutical Sciences
Background:
- Insulin therapy is crucial for managing hyperglycemia in type 1 and type 2 diabetes.
- Existing insulin delivery methods (syringes, pens, pumps) are invasive, causing patient discomfort and adherence issues.
Purpose of the Study:
- To review emerging non-invasive insulin delivery systems.
- To explore novel concepts for future insulin administration.
Main Methods:
- Literature review of current and developing insulin delivery technologies.
- Focus on non-invasive approaches such as artificial pancreas, transdermal, buccal, oral, and pulmonary routes.
Main Results:
- Invasive methods like injections and pumps remain standard but have drawbacks.
- Non-invasive methods are under active investigation to overcome the limitations of traditional delivery.
Conclusions:
- Advancements in non-invasive insulin delivery systems are critical for improving patient quality of life.
- Future research should focus on developing safe and effective alternative routes for insulin administration.
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