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Imaging for deep brain stimulation: The zona incerta at 7 Tesla
Hans U Kerl1, Lars Gerigk, Marc A Brockmann
1Hans U Kerl, Marc A Brockmann, Sonia Huck, Mansour Al-Zghloul, Christoph Groden, Ingo S Nölte, Department of Neuroradiology, University Medical Center Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
World Journal of Radiology
|March 16, 2013
Summary
FLASH2D-T2Star MRI at 7.0 Tesla offers optimal visualization of the rostral zona incerta (rZI). This technique enhances pre-stereotactic targeting accuracy for neurosurgical procedures.
Area of Science:
- Neuroimaging
- Radiology
- Stereotactic Surgery
Background:
- The zona incerta (ZI) is a challenging deep brain structure for pre-stereotactic visualization.
- Advanced magnetic resonance imaging (MRI) techniques are crucial for accurate targeting.
Purpose of the Study:
- To evaluate various 7.0 Tesla (T) MRI sequences for optimal pre-stereotactic visualization of the zona incerta (ZI).
Main Methods:
- Qualitative and quantitative assessment of T2-turbo spin-echo (T2-TSE), T1-weighted gradient-echo, FLASH2D-T2Star, and susceptibility-weighted imaging (SWI) at 7.0 T.
- Image quality, delineation, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were analyzed.
- Coronal FLASH2D-T2Star images were co-registered with the Schaltenbrand-Wahren stereotactic atlas.
Main Results:
- Coronal FLASH2D-T2Star imaging provided the best and most reliable visualization of the rostral ZI (rZI).
- FLASH2D-T2Star and SWI showed significantly higher CNR for the rZI compared to T2-TSE.
- The caudal ZI was not definable with any tested sequence.
Conclusions:
- FLASH2D-T2Star imaging, especially in the coronal view, is the optimal method for visualizing the rZI at 7.0 T.
- This technique improves pre-stereotactic targeting of the ZI, potentially enhancing surgical precision.
