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Related Experiment Videos

Blood sampling through umbilical catheters.

D R Brown, L J Fenton, R C Tsang

    Pediatrics
    |February 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Umbilical catheter blood draws can reliably measure pH, sodium, potassium, and glucose if a small initial sample is discarded. Larger catheters may affect glucose measurement accuracy.

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    Area of Science:

    • Neonatal Medicine
    • Clinical Chemistry
    • Medical Device Engineering

    Background:

    • Umbilical catheters are crucial for neonatal intensive care, enabling frequent blood sampling.
    • Accurate chemical analysis of blood samples is vital for effective patient management.
    • Potential for sample dilution exists due to infusates within catheters.

    Purpose of the Study:

    • To evaluate the accuracy of chemical blood analyses performed on samples drawn via umbilical catheters.
    • To determine the minimum discard volume required for reliable results across different catheter sizes.

    Main Methods:

    • An in vitro study simulating blood withdrawal through 3.5, 5, and 8 French umbilical catheters.
    • Catheters contained solutions of dextrose, sodium bicarbonate, and potassium.

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  • Blood samples were analyzed for pH, sodium, potassium, and glucose after discarding specific volumes (4-6 ml).

    • Main Results:

    • Accurate pH, sodium, potassium, and glucose measurements were achieved with 3.5 and 5 French catheters after discarding 4 ml.
    • Accurate pH, sodium, and potassium measurements were obtained with the 8 French catheter after discarding 6 ml.
    • Plasma glucose measurements remained inaccurate with the 8 French catheter even after discarding 6 ml.

    Conclusions:

    • Discarding an initial 4 ml of blood ensures reliable chemical analysis for smaller umbilical catheters (≤5 Fr).
    • Larger umbilical catheters (8 Fr) may compromise glucose measurement accuracy due to potential dilution effects.
    • Clinical laboratories and neonatal units should consider catheter size and discard volumes for accurate blood gas and electrolyte testing.