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Updated: May 13, 2026

The C. elegans Excretory Canal as a Model for Intracellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis in a Single Cell: labeling by GFP-fusions, RNAi Interaction Screen and Imaging
10:30

The C. elegans Excretory Canal as a Model for Intracellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis in a Single Cell: labeling by GFP-fusions, RNAi Interaction Screen and Imaging

Published on: October 3, 2017

Mechanical control of epithelial lumen formation

Alejo E Rodríguez-Fraticelli1, Fernando Martín-Belmonte

  • 1Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Madrid, Spain.

Small Gtpases
|March 21, 2013
PubMed
Summary

Cell confinement guides epithelial organ development by controlling cell polarity and lumen formation. Mechanical cues regulate cell contractility and organelle positioning, crucial for morphogenesis and disease understanding.

Keywords:
MDCKRabRhociliogenesisepithelial cell polaritylumen formationmechanotransduction

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