Super giant squamous cell carcinomas

Squamous cell carcinomas (SCCs) larger than 2 cm in diameter are associated with a greater risk for disfigurement, local recurrence, and metastasis. Giant SCCs are rare. They may develop near aesthetically and functionally important structures and infiltrate them. Treatment may be difficult with the need for large tissue resections and complex surgical reconstruction, with important repercussions on the quality of life of patients. We report 2 cases of super giant SCCs with long-standing evolution that were successfully treated with surgical excision and followed for 24 months posttreatment without signs of local recurrence and/or metastasis.