[Natural history and outcomes of atrial fibrillation]

François Brigadeau1, Dominique Lacroix

  • 1Hôpital cardiologique, CHRU de Lille, 59037 Lille Cedex, France. f-brigadeau@chru-lille.fr

La Revue Du Praticien
|March 22, 2013
PubMed

Insights

Atrial fibrillation (AF) often presents without symptoms, but its complications like stroke and heart failure significantly increase mortality risk. Antithrombotic treatment for AF focuses on overall risk, not symptom perception.

Area of Science:

  • Cardiology
  • Neurology

Context:

  • Atrial fibrillation (AF) frequently occurs asymptomatically, with the initial presentation potentially being a severe complication.
  • The progression of AF from paroxysmal to persistent forms is unpredictable.
  • Antithrombotic therapy decisions in AF are based on global thromboembolic risk assessment, independent of patient-reported symptoms or rhythm status.

Purpose:

  • To highlight the silent nature of atrial fibrillation and its potential for severe, unheralded complications.
  • To underscore the critical link between atrial fibrillation and major adverse events, including stroke and heart failure.

Summary:

  • Atrial fibrillation (AF) often lacks early symptoms, with the first manifestation frequently being a stroke.
  • AF-related strokes are associated with high mortality and can contribute to cognitive decline.
  • Heart failure is another common complication of AF, sharing etiological factors and contributing to increased mortality.
  • While less life-threatening, AF significantly impairs quality of life and leads to frequent hospitalizations.

Impact:

  • Emphasizes the need for proactive risk assessment and management in all patients with atrial fibrillation, regardless of symptoms.
  • Underscores the severe consequences of AF, including stroke and heart failure, which elevate overall mortality.
  • Highlights the significant impact of AF on patient quality of life and healthcare utilization.

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