Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Crashing by design: Utilizing DNA damage for MCC differentiation.

Trends in cell biology·2026
Same author

Sidekick2 facilitates multiciliated cell penetration through multicellular adherens junctions.

bioRxiv : the preprint server for biology·2026
Same author

Three types of actomyosin rings within a common cytoplasm exhibit distinct modes of contractility.

Molecular biology of the cell·2025
Same author

Author Correction: Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds.

Nature biomedical engineering·2025
Same author

Animal septins contain functional transmembrane domains.

Current biology : CB·2025
Same author

Lessons on the force-form-function connection in cell biology from modeling a syncytial germline.

Current opinion in cell biology·2025
Same journal

1,2-Aminothiol-specific conjugation for dual-color fluorescent labeling via ultrafast TAMM conjugates.

Methods in enzymology·2026
Same journal

Nitrone dipoles in bioorthogonal chemistry applications.

Methods in enzymology·2026
Same journal

Bioorthogonal labeling of sialic acid isomers for detection of glycoconjugates by mass spectrometry imaging and microscopy.

Methods in enzymology·2026
Same journal

Bioorthogonal photocatalytic proximity labeling for quantitative mapping of cell-cell interactions.

Methods in enzymology·2026
Same journal

inCu-click: Enabling copper-catalyzed click chemistry inside living cells.

Methods in enzymology·2026
Same journal

Site-specific antibody labeling via endo-S2 mediated Fc glycan remodeling.

Methods in enzymology·2026
See all related articles

Related Experiment Video

Updated: May 13, 2026

Mucociliary Epithelial Organoids from Xenopus Embryonic Cells: Generation, Culture and High-Resolution Live Imaging
07:44

Mucociliary Epithelial Organoids from Xenopus Embryonic Cells: Generation, Culture and High-Resolution Live Imaging

Published on: July 28, 2020

Using Xenopus skin to study cilia development and function.

Michael E Werner1, Brian J Mitchell

  • 1Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

Methods in Enzymology
|March 26, 2013
PubMed
Summary
This summary is machine-generated.

Xenopus larval skin offers a powerful model for studying cilia development and function. This system facilitates research into cilia-based cell signaling and fluid movement, benefiting diverse biological questions.

More Related Videos

Live-cell Imaging and Quantitative Analysis of Embryonic Epithelial Cells in Xenopus laevis
06:51

Live-cell Imaging and Quantitative Analysis of Embryonic Epithelial Cells in Xenopus laevis

Published on: May 23, 2010

Electroporation of Craniofacial Mesenchyme
07:23

Electroporation of Craniofacial Mesenchyme

Published on: November 28, 2011

Related Experiment Videos

Last Updated: May 13, 2026

Mucociliary Epithelial Organoids from Xenopus Embryonic Cells: Generation, Culture and High-Resolution Live Imaging
07:44

Mucociliary Epithelial Organoids from Xenopus Embryonic Cells: Generation, Culture and High-Resolution Live Imaging

Published on: July 28, 2020

Live-cell Imaging and Quantitative Analysis of Embryonic Epithelial Cells in Xenopus laevis
06:51

Live-cell Imaging and Quantitative Analysis of Embryonic Epithelial Cells in Xenopus laevis

Published on: May 23, 2010

Electroporation of Craniofacial Mesenchyme
07:23

Electroporation of Craniofacial Mesenchyme

Published on: November 28, 2011

Area of Science:

  • Developmental Biology
  • Cell Biology
  • Biophysics

Background:

  • Cilia are vital cellular structures involved in signaling and fluid transport across diverse organisms.
  • Existing model systems have limitations in analyzing cilia development and function comprehensively.

Purpose of the Study:

  • To introduce Xenopus larval skin as an effective model system for studying ciliogenesis and ciliary function.
  • To highlight molecular, embryological, and imaging techniques applicable to cilia research.

Main Methods:

  • Utilizing Xenopus larval skin for embryological manipulations.
  • Employing molecular techniques for genetic studies.
  • Implementing advanced imaging for visualizing ciliary beating and fluid dynamics.

Main Results:

  • Demonstrated the utility of Xenopus larval skin for observing polarized ciliary beating.
  • Showcased methods for analyzing directed fluid flow generated by cilia.
  • Established a versatile platform for cilia research.

Conclusions:

  • Xenopus larval skin provides a robust and adaptable model for investigating ciliogenesis and ciliary function.
  • The described techniques offer broad applicability to various cilia-related research areas.
  • This model system has the potential to advance understanding of cilia's role in health and disease.