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Updated: May 12, 2026
07:45
Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
Published on: November 6, 2018
Dressings for superficial and partial thickness burns
Jason Wasiak1, Heather Cleland, Fiona Campbell
1Victorian Adult Burns Service and School of Public Health and Preventative Medicine, Monash University, The Alfred Hospital,Melbourne, Australia. J.Wasiak@alfred.org.au.
The Cochrane Database of Systematic Reviews
|April 2, 2013
Summary
Silver sulphadiazine dressings showed poorer healing outcomes for burns compared to biosynthetic, silicon-coated, and silver dressings. Hydrogel dressings promoted faster healing than usual care, despite limited high-quality evidence.
Area of Science:
- Wound healing research
- Dermatology
- Biomaterials science
Background:
- Burn wounds are complex injuries with local and systemic effects.
- Effective treatment of partial thickness burns focuses on promoting healing.
- Advancements in wound healing understanding drive the development of novel dressings.
Purpose of the Study:
- To assess the impact of various burn wound dressings on superficial and partial thickness burns.
- Evaluate the efficacy of different dressing types in burn wound management.
Main Methods:
- Systematic review of randomized controlled trials (RCTs) evaluating burn wound dressings.
- Searched multiple databases including Cochrane Wounds Group Register, CENTRAL, MEDLINE, EMBASE, and CINAHL.
- Data extraction and internal validity assessment by two independent authors.
Main Results:
- Thirty RCTs were included, with generally poor trial quality and reporting.
- Silver sulphadiazine (SSD) was linked to inferior healing outcomes compared to biosynthetic, silver, and silicon-coated dressings.
- Hydrogel dressings demonstrated accelerated healing compared to usual care.
Conclusions:
- High-quality evidence on burn wound dressing effectiveness is scarce.
- Most included studies were at risk of bias, limiting firm conclusions.
- While SSD showed poorer outcomes, hydrogels appeared beneficial, but further research is needed.
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