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Updated: May 12, 2026

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
Published on: August 28, 2015
Amphiphilic polymers bearing gluconolactone moieties: synthesis and long side-chain crystalline behavior
María L Cerrada1, Vanesa Bordegé, Alexandra Muñoz-Bonilla
1Instituto de Ciencia y Tecnología de Polímeros (ICTP-CSIC), C/ Juan de la Cierva 3, 28006 Madrid, Spain.
Abstract:
The synthesis and characterization of amphiphilic polymers bearing gluconolactone moieties has been described. In a first step, an unprotected glycomonomer 2-[({[4-(d-gluconamid-N-yl)butyl]amino}carbonyl)oxy]ethyl acrylate, HEAG, has been synthesized. Posterior, this glycomonomer has been copolymerized with methyl methacrylate at different compositions and the kinetic behavior has been also studied calculating the monomer reactivity ratios by Kelen-Tüdös extended equation. In addition, the long side-chain crystalline behavior of these carbohydrate-based copolymers with high composition of glycomonomer has been examined by using conventional and modulated differential scanning calorimetry and X-ray diffraction measurements. At the same time, the phase separation behavior of carbohydrate-based copolymers with lower HEAG content has been determined by their glass transition temperature measurements. Finally, the thermal stability of all these amphiphilic copolymers has been evaluated by thermogravimetric analysis.
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