Related Experiment Video
Updated: May 12, 2026

05:24
Preparation of Mechanically Stable Self-Assembled Peptides Hydrogels
Published on: September 6, 2024
Synthesis of peptoid based small molecular gelators by a multiple component reaction
Hari P R Mangunuru1, Hao Yang, Guijun Wang
1Department of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA 23529, USA.
Abstract:
We report the synthesis and self-assembling properties of a new class of tripeptoids synthesized by a one-pot Ugi reaction from simple starting materials. Among the focused library of tripeptoids synthesized, several efficient low molecular weight gelators were obtained for aqueous DMSO and ethanol mixtures.
Related Concept Videos
Step-Growth Polymerization: Overview
Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
Many natural and synthetic polymers are produced by...
Peptidoglycan Synthesis
Structure of PeptidoglycanPeptidoglycan is a vital structural component of the bacterial cell wall, providing mechanical strength and shape to the cell. It consists of repeating units of two sugars—N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM)—linked by β-1,4 glycosidic bonds. These sugar chains are cross-linked by short peptide chains, forming a mesh-like polymer that surrounds the bacterial plasma membrane.Cytoplasmic Phase – Precursor SynthesisPeptidoglycan biosynthesis begins in...

