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Updated: May 12, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Amide-controlled highly selective catalytic borylcupration of allenes
Weiming Yuan1, Xue Zhang, Yihua Yu
1Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, 3663 North Zhongshan Lu, Shanghai 200062, PR China.
Abstract:
A novel copper-catalyzed, highly regio- and stereoselective borylcupration of substituted 2,3-allenamides with bis(pinacolato)diboron producing Z-β-borylated β,γ-unsaturated enoamides has been demonstrated. Due to the unique effect of the amide-group, perfect regio- and stereoselectivity and good to excellent yields have been achieved, which were rationalized by a DFT study.
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