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Measurement of Tumor T2* Relaxation Times after Iron Oxide Nanoparticle Administration
Published on: May 19, 2023
An analysis of T2 mapping on brain tumors
Kanji Nakai1, Hiroshi Nawashiro, Katsuji Shima
1Department of Neurosurgery, Fukuoka University Chikushi Hospital, Fukuoka, Japan. neuroivr@gmail.com
Purpose:
Vasogenic edema on glioblastoma multiforme (GBM) or a metastatic brain tumor (METS) may have different T2 relaxation time values because it involves an increased water component. In this study, we assessed the diagnostic utility of T2 mapping techniques in distinguishing GBM from METS.
Materials And Methods:
We studied a glioblastoma (GBM) patient and a metastatic brain tumor (METS) patient who had not undergone previous surgery or treatment. All MR imaging was carried out using a 3.0-T whole-body unit, and axial T2 maps were generated with five TEs (TE = 20, 40, 60, 80, and 100 ms). Data were analyzed by using image processing and analysis software.
Results:
The T2 map of a GBM case showed that the -peritumoral area at a T2 relaxation time of 120-160 ms is prominent compared with the area at 210-240 ms. In contrast, the peritumoral area at 210-240 ms was prominent compared with the area at 120-160 ms in a METS case.
Conclusion:
The distribution of T2 relaxation time in the peritumoral area shows different patterns in glioblastomas and metastatic brain tumors.
