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Related Experiment Video

Updated: May 12, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

The aetiology underlying sinus headaches.

Mustafa Kaymakci¹, Halil Ibrahim Cikriklar, Gunes Pay

¹Department of Otorhinolaryngology, Head and Neck Surgery, Balikesir University, Balikesir, Turkey. mbkaymak@yahoo.com

The Journal of International Medical Research

|April 10, 2013

Summary

Many sinus headaches are misdiagnosed neurovascular events, like migraines. Proper diagnosis using endoscopy and CT scans can reduce unnecessary sinusitis treatments for patients experiencing facial pain.

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Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

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Published on: July 29, 2021

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Last Updated: May 12, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

Published on: July 29, 2021

Area of Science:

Otorhinolaryngology
Neurology
Headache Medicine

Background:

Sinus headaches are often misdiagnosed as sinusitis, leading to unnecessary treatments.
Patients report pain and pressure around sinuses and periorbital areas.

Purpose of the Study:

Investigate the underlying causes of sinus headaches in patients with negative endoscopic or CT scan findings.
Differentiate primary headaches from actual sinus pathology.

Main Methods:

Prospective, multicenter study of 98 patients presenting with sinus headache.
Exclusion of patients with sinonasal pathology via endoscopic and radiological examination.
Follow-up for 3 months to assess treatment response based on International Headache Society criteria.

Main Results:

Neurovascular events were identified as the primary cause of misdiagnosed sinus headaches.
Accompanying symptoms like nasal obstruction and discharge contributed to misdiagnosis.

Conclusions:

Improved understanding of vascular headaches, particularly migraines, is crucial.
Comprehensive endoscopic and CT evaluations can significantly reduce misdiagnosis rates for sinus headaches.