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Related Experiment Video

Updated: May 12, 2026

Infant Auditory Processing and Event-related Brain Oscillations

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

Age differences in thalamic low-frequency fluctuations.

Mara Mather¹, Lin Nga

¹Davis School of Gerontology, University of Southern California, California 90089, USA.

|April 11, 2013

Summary

This summary is machine-generated.

Aging alters thalamic brain activity. Older adults exhibit greater low-frequency oscillations in the thalamus, impacting cognitive processes and brain communication. This research highlights age-related changes in neural dynamics.

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Last Updated: May 12, 2026

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Published on: May 19, 2016

Area of Science:

Neuroscience
Cognitive Aging Research

Background:

The thalamus is crucial for cognitive functions and inter-regional brain communication.
Understanding age-related changes in thalamic function is vital due to its role in cognition.

Purpose of the Study:

To investigate age differences in thalamic low-frequency fluctuations during resting-state.
To determine how aging affects the oscillatory activity within the thalamus.

Main Methods:

Analysis of independent datasets examining resting-state functional magnetic resonance imaging (fMRI) data.
Focus on low-frequency oscillations (0.01-0.10 Hz) within the thalamus.

Main Results:

Older adults showed a greater amplitude of low-frequency oscillations in the thalamus compared to younger adults.
This age-related increase was most prominent at the lowest frequencies (0.010-0.027 Hz).
Younger adults exhibited greater amplitude in higher low-frequency ranges (0.198-0.250 Hz) than older adults.

Conclusions:

Aging is associated with distinct shifts in thalamic low-frequency oscillatory activity.
These alterations in thalamic dynamics may influence coordinated brain activity and cognitive performance in aging.