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Harnessing DCs by substance P

Akira Takashima1

  • 1University of Toledo.

Blood
|April 13, 2013
PubMed

In this issue of Blood, Janelsins et al report that substance P (SP)–treated dendritic cells (DCs) efficiently home to lymph nodes, where they induce inflammatory DCs to produce interleukin-12 (IL-12), thereby promoting type 1 polarized immunity.

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