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Photoletter to the editor: Disseminated histoplasmosis with initial oral manifestations

Surabhi Sinha1, Kabir Sardana, Vijay K Garg

  • 1Department of Dermatology, S.T.D. and Leprosy, Dr. RML Hospital, New Delhi - 110001, India;

Journal of Dermatological Case Reports
|April 13, 2013
PubMed

Insights

Oral lesions can be the first sign of histoplasmosis, a rare fungal infection. This case highlights disseminated histoplasmosis presenting initially with oral manifestations.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Oral Medicine

Background:

  • Histoplasmosis is a systemic fungal infection caused by Histoplasma capsulatum.
  • Clinical presentations vary widely, but oral involvement is uncommon.
  • Oral lesions can occur in disseminated disease or as isolated findings.

Purpose of the Study:

  • To report a rare case of disseminated histoplasmosis.
  • To emphasize oral lesions as the initial presentation.
  • To highlight the diagnostic challenge of unusual initial manifestations.

Main Methods:

  • Case report of a patient with disseminated histoplasmosis.
  • Clinical examination focusing on oral lesions.
  • Diagnostic workup including microbiological and histopathological analysis.

Main Results:

  • The patient presented with oral lesions as the first noticeable symptom.
  • Disseminated histoplasmosis was confirmed through diagnostic tests.
  • The oral lesions were indicative of the systemic spread of the fungal infection.

Conclusions:

  • Oral manifestations can be the primary presenting sign of disseminated histoplasmosis.
  • Early recognition of oral lesions is crucial for timely diagnosis and treatment.
  • This case underscores the importance of considering fungal infections in patients with unexplained oral findings.
Keywords:
AIDSFungal infectionHIVhistoplasmamucous membraneoral mucosatongue

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