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Splanchnic venous thrombosis and pancreatitis
Nikhil A Nadkarni1, Sahil Khanna, Santhi Swaroop Vege
1Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA.
Pancreas
|April 17, 2013
Summary
Pancreatitis can cause splanchnic venous thrombosis, especially in the splenic vein. This review covers the causes, diagnosis, and treatment of this complication in acute and chronic pancreatitis.
Area of Science:
- Gastroenterology and Hepatology
- Vascular Surgery
- Internal Medicine
Background:
- Pancreatitis is an inflammatory condition with systemic effects.
- A local complication is splanchnic venous thrombosis, primarily affecting the splenic vein.
- Existing literature on pancreatitis-associated thrombosis is limited.
Purpose of the Study:
- To provide a comprehensive overview of splanchnic venous thrombosis in pancreatitis.
- To discuss the mechanisms, pathophysiology, diagnosis, and management of this complication.
- To consolidate current knowledge for clinicians and researchers.
Main Methods:
- Literature review of pancreatitis and splanchnic venous thrombosis.
- Synthesis of information on thrombosis mechanisms and pathophysiology.
- Analysis of diagnostic modalities and treatment strategies.
Main Results:
- Splanchnic venous thrombosis is a significant local manifestation of pancreatitis.
- The splenic vein is the most commonly involved vessel.
- The review details the multifaceted approach to managing this complication.
Conclusions:
- Splanchnic venous thrombosis requires careful consideration in pancreatitis management.
- Understanding the pathophysiology aids in timely diagnosis and effective treatment.
- Further research is warranted to optimize therapeutic outcomes.
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