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Updated: May 12, 2026

Preparation and Evaluation of 99mTc-labeled Tridentate Chelates for Pre-targeting Using Bioorthogonal Chemistry
Published on: February 4, 2017
Extraosseous accumulation of bone scan tracer (99m)Tc-methylene diphosphonate in a phlebolith
Mukta Kulkarni1, Archi Agrawal, Anand Zade
1Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Parel, Mumbai, India.
Abstract:
Uptake in non-osseous, non-urologic tissues is occasionally found in the performance of bone scintigraphy. These uptakes reflect an atypical interaction between the radiopharmaceutical and the patient. Knowledge of the rare extraskeletal uptakes and their clinical relevance helps in better interpretation of bone scans. We report an unusual occurrence of extraosseous accumulation of (99m)Tc-methylene diphosphonate in a phlebolith in bone scan, confirmed with the aid of photon emission computed tomography and computed tomography.
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