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08:50
Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
Published on: February 9, 2019
Optical coherence tomography: clinical applications in medical practice
Abdullah Al-Mujaini1, Upender K Wali, Sitara Azeem
1Department of Ophthalmology, College of Medicine and Health Sciences, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman.
Oman Medical Journal
|April 20, 2013
Summary
Optical Coherence Tomography (OCT) provides high-resolution, real-time imaging of biological tissues. This technology enhances disease diagnosis and monitoring, particularly in ophthalmology and systemic conditions.
Area of Science:
- Biomedical Imaging
- Ophthalmology
- Medical Technology
Background:
- Optical Coherence Tomography (OCT) combines physics and clinical practice.
- Cross-sectional imaging revolutionized OCT's medical applications.
- OCT is a non-contact, high-resolution biomicroscopic device for real-time in vivo imaging.
Purpose of the Study:
- To highlight the impact of OCT in medical diagnosis and research.
- To showcase OCT's capabilities in visualizing biological tissues.
- To emphasize OCT's role in managing ocular and systemic diseases.
Main Methods:
- Utilizes low-coherence interferometry based on light reflection and backscattering.
- Achieves spatial resolution as low as 3 microns for cellular-level tissue study.
- Employs digitalization and advanced software for data management.
Main Results:
- Revolutionized diagnosis, follow-up, and treatment response assessment.
- Improved sensitivity and specificity in diagnosing ocular pathologies.
- Facilitated early detection of systemic diseases like diabetes, hypertension, and neurological disorders.
Conclusions:
- OCT is an invaluable tool for diagnosing and monitoring eye diseases.
- OCT aids in identifying secondary ocular manifestations of systemic conditions.
- OCT assists in early diagnosis of diseases like multiple sclerosis and drug-induced retinopathies.
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