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Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients
Published on: August 2, 2024
Corneal sensitivity after topical bromfenac sodium eye-drop instillation
Kaori Yanai1, Jane Huang, Kazuaki Kadonosono
1Department of Ophthalmology, Fukuoka University School of Medicine, Fukuoka, Japan.
Clinical Ophthalmology (Auckland, N.Z.)
|April 30, 2013
Summary
Bromfenac sodium eye drops demonstrated safety in healthy individuals, showing no adverse effects on corneal sensitivity or tear secretion over a 1-month trial. Further studies are needed for patients with ocular conditions.
Area of Science:
- Ophthalmology
- Pharmacology
Background:
- Ophthalmic non-steroidal anti-inflammatory drugs (NSAIDs) are widely used.
- Assessing the safety profile of topical medications is crucial for patient care.
Purpose of the Study:
- To evaluate the safety of bromfenac sodium eye drops.
- Assessed impact on corneal sensitivity and tear secretion in healthy subjects.
Main Methods:
- Prospective, single-blind, parallel clinical study.
- Ten healthy volunteers received bromfenac sodium or artificial tears twice daily for 28 days.
- Corneal sensitivity (Cochet-Bonnet esthesiometer) and tear secretion (Schirmer's test) were measured.
Main Results:
- No significant differences in corneal sensitivity were found between bromfenac and artificial tear groups.
- Tear secretion rates remained comparable between the two treatment groups throughout the study.
Conclusions:
- Bromfenac sodium eye drops appear safe for corneal sensitivity and tear secretion in individuals with healthy ocular surfaces.
- Further research is warranted to confirm safety in patients with ocular inflammatory disorders or post-surgical conditions.
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