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Updated: May 11, 2026

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum
Published on: December 8, 2023
[Chemical constituents of Dipsacus asper]
Zi-Gang Yang1, Kun Ding, Gang Xu
1Yunnan Agricultural University/Yunnan Research Center on Good Agricultural Practice for Dominant Chinese Medicinal Materials, Kunming 650201, China. yzg_10@163.com
Objective:
To study the chemical constituents of Dipsacus asper.
Methods:
Column chromatography on Silica gel and RP-C18 were applied for isolation and purification of the constituents. Their structures were identified by spectral and chemical methods.
Results:
From the crude MeOH fraction of Dipsacus asper, 12 compounds were isolated and identified as Sucrose (1), beta-sitosterol (2), Oleanic acid (3), Triplostoside A (4), Loganin (5), Loganin acid (6), Sweroside (7), Epi-vogeloside ( 8), Vogeloside (9), Akebiasaponin D(10), Cauloside A(11),7-Deoxyloganic acid (12).
Conclusion:
Compounds 8, 9, 12 are isolated from this plant for the first time.
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