Related Experiment Video
Updated: May 11, 2026
05:34
5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
Published on: April 4, 2025
Severe periodontitis associated with chronic kidney disease
1Department of Dentistry, Vardhaman Mahavir Medical College and Safdarjang Hospital, New Delhi, India.
Journal of Indian Society of Periodontology
|May 2, 2013
Summary
Data on chronic periodontitis and chronic kidney disease (CKD) in India is limited. This case highlights unusual gingival overgrowth in a CKD patient, indicating a need for further research into the disease
Area of Science:
- Periodontology
- Nephrology
- Oral Medicine
Background:
- Limited data exists on the prevalence and severity of chronic periodontitis in Indian patients with chronic kidney disease (CKD).
- Understanding the interplay between periodontal disease and CKD is crucial for comprehensive patient care.
Observation:
- A case of severe periodontitis associated with CKD is presented.
- The patient exhibited unusual inflammatory gingival overgrowth that was resistant to conventional treatment.
Findings:
- The case demonstrates a complex interaction between severe periodontitis and chronic kidney disease.
- Persistent gingival overgrowth suggests potential unique pathogenetic mechanisms in CKD patients.
Implications:
- Highlights a significant gap in the understanding of periodontal disease etiopathogenesis in CKD patients.
- Emphasizes the need for further research to elucidate the relationship between CKD and periodontal health.
- Suggests potential for novel therapeutic approaches targeting the specific mechanisms involved.
Related Concept Videos
01:25Chronic Kidney Disease I: Introduction
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
01:28Chronic Kidney Disease III: Interprofessional Care
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
01:24Chronic Kidney Disease II: Clinical Manifestations
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
01:28Diabetic Nephropathy
Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...
01:10Nephrons
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma happens...
01:29Acute Kidney Injury III: Clinical Manifestations
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...