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Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection
Published on: March 14, 2019
Capnocytophaga spp. involvement in bone infections: a review
Caroline Piau1, Cédric Arvieux, Martine Bonnaure-Mallet
1Laboratoire de Bactériologie, Rennes University Hospital, rue Henri Le Guilloux, 35043 Rennes, France.
Abstract:
Capnocytophaga are commensal gliding bacteria that are isolated from human and animal oral flora and are responsible for infections both in immunocompromised and immunocompetent hosts. Accumulation of microbial plaque, loss of collagen attachment, and alveolar bone resorption around the tooth can lead to local Capnocytophaga spp. bone infections. These capnophilic bacteria, from oral sources or following domestic animal bites, are also causative agents of bacteraemia and systemic infections as well as osteomyelitis, septic arthritis, and infections on implants and devices. The present literature review describes the main aetiologies of bone infections due to Capnocytophaga spp., the cellular mechanisms involved, methods used for diagnosis, antimicrobial susceptibility, and effective treatments.
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