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Choroidal thickness in childhood.

Scott A Read1, Michael J Collins, Stephen J Vincent

  • 1Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia. sa.read@qut.edu.au

Investigative Ophthalmology & Visual Science
|May 9, 2013
PubMed
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Choroidal thickness (ChT) in children increases with age and varies across the posterior pole, reflecting normal eye growth. This study measured ChT in healthy pediatric eyes using optical coherence tomography (OCT).

Area of Science:

  • Ophthalmology
  • Pediatric Optometry
  • Ocular Imaging

Background:

  • Choroidal thickness (ChT) is a key indicator of ocular health.
  • Understanding normal ChT development in children is crucial for identifying potential visual impairments.
  • Previous studies have not fully detailed the spatial distribution of ChT in healthy pediatric populations.

Purpose of the Study:

  • To examine choroidal thickness (ChT) and its spatial distribution in the posterior pole of healthy children.
  • To investigate the relationship between ChT and age in pediatric subjects with minimal refractive error.
  • To establish normative data for ChT in childhood.

Main Methods:

  • Spectral domain optical coherence tomography (OCT) was used to assess ChT in 194 children (ages 4-12).
Keywords:
choroidoptical coherence tomographypediatricrefractive error

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  • OCT scans were acquired along radial lines centered on the fovea, with image processing to enhance chorioscleral visibility.
  • Manual segmentation by masked observers determined ChT at the foveal center and across perifoveal zones.
  • Main Results:

    • Average subfoveal ChT was 330 ± 65 μm, significantly influenced by age (P=0.04).
    • ChT was thinner in younger children (4-6 years) compared to older groups.
    • Choroidal thickness varied spatially, being thicker centrally and thinner nasally/inferiorly; age, axial length, and anterior chamber depth were significant predictors.

    Conclusions:

    • Choroidal thickness significantly increases from early childhood to adolescence.
    • This age-related increase in ChT is a normal aspect of childhood eye growth.
    • The findings provide valuable normative data for pediatric ocular development.