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Diabetic Retinopathy

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

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[Relationship between macular morphology and visual function in diabetic macular edema].

Hui-yi Jin¹, Hai-yun Liu, Kun Liu

¹Department of Ophthalmology, Shanghai Jiaotong University Affiliated First People's Hospital, Shanghai 200080, China.

Zhonghua Yi Xue Za Zhi

|May 11, 2013

Summary

Diabetic macular edema causes retinal changes that worsen with disease progression. Microperimetry is sensitive for detecting early visual function decline in diabetic macular edema.

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Area of Science:

Ophthalmology
Retinal Diseases
Diabetic Retinopathy

Context:

Diabetic macular edema (DME) is a common complication of diabetic retinopathy.
Understanding the relationship between structural and functional changes in DME is crucial for patient management.

Purpose:

To investigate the relationship between macular morphology and visual function in different stages of diabetic macular edema.
To assess the utility of microperimetry in evaluating visual function in DME.

Summary:

Macular thickness increased and sensitivity decreased significantly from no edema to clinically significant macular edema.
Visual acuity declined in the CSME group, with no difference between no edema and non-clinically significant edema groups.
Microperimetry showed strong correlations with visual acuity and macular thickness, particularly in the CSME group.

Impact:

Retinal morphologic and functional changes occur early in DME and are linked as the disease progresses.
Microperimetry is a sensitive tool for evaluating visual function changes in early DME, correlating well with visual acuity.