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Toward clinical application of the Keap1-Nrf2 pathway

Takafumi Suzuki1, Hozumi Motohashi, Masayuki Yamamoto

  • 1Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.

Trends in Pharmacological Sciences
|May 14, 2013
PubMed
Summary

The Keap1-Nrf2 pathway protects cells from toxins but cancer cells exploit it for growth. Targeting this pathway offers a promising strategy for cancer therapy and improving human health.

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