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Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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[Characteristics of T lymphocyte subpopulations]

Paulina Niedźwiedzka-Rystwej1, Beata Tokarz-Deptuła, Wiesław Deptuła

  • 1Katedra Immunologii, Wydział Biologii, Uniwersytet Szczeciński, Szczecin, Poland.

Postepy Higieny I Medycyny Doswiadczalnej (Online)
|May 14, 2013
PubMed

The paper describes the characteristics, receptor profile and functions of T lymphocyte subpopulations (helper, cytotoxic, regulatory, memory and others). Among T helper cells one can enumerate Th0, Th1, Th2, Th9, Th17, Th22, T(FH) and nTh2, while T cytotoxic cells include Tc, NKT, Tγδ, and T CD8αα (IEL). Among regulatory cells there are nTreg, iTreg, T(R)1, and iT(R)35, as well as T lymphocytes with CD8, such as CD8+CD122+, CD8+CD28-, and CD11c+CD8+. And among memory T cells there are Tcm and Tem. Moreover, there are some so-called other T cells, such as Tn (T αβ CD4+ and T αβ CD8+), T exhausted and T anergic.

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