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[Dose titration with Euphylong following prior determination of serum concentration in the steady state]
D Schnabel1, S von Treufels, M Oellerich
1Abt. Pneumologie, Medizinische Universitätsklinik, Homburg/Saar.
Pneumologie (Stuttgart, Germany)
|February 1, 1990
Abstract:
Euphylong is a theophylline preparation with new galenic slow-release design (micropellets in a capsule), developed for daily single-dose administration in the evening. It has been shown that the majority of patients with bronchial asthma, chronic obstructive bronchitis or emphysema who receive a single evening dose of Euphylong have a theophylline serum concentration that remains within the therapeutic range for 24 hours when the theophylline serum concentration measured at 8 a.m. under steady-state conditions is found to lie within the therapeutic range.