Related Experiment Video
Updated: May 11, 2026

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
Published on: November 21, 2017
Subcutaneous fat necrosis after selective head cooling in an infant
Toru Kuboi1, Takashi Kusaka, Kaoru Okazaki
1Department of Neonatology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
Abstract:
Hypoxic-ischemic encephalopathy in neonates causes irreversible damage to tissue and organs and results in multiple organ failure and poor outcome. Therapeutic hypothermia is the most effective therapy in neonates with hypoxic-ischemic encephalopathy. We report here a case of subcutaneous fat necrosis (SCFN) after therapeutic hypothermia by selective head cooling. Selective head cooling was provided for 72 h after birth. SCFN developed on the patient's cheeks and back at the age of 21 days. Thus, SCFN may be caused by selective head cooling, similarly to whole-body cooling.
Related Concept Videos
Decreased Body Temperature
Cellular Injury IV: Necrosis
Methods of reducing fever
Pharmacological Methods of Reducing Fever:

