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Updated: May 11, 2026

The Nijmegen Hemostasis Assay: Simultaneous Fluorogenic Measurement of Thrombin and Plasmin Generation in a Single Well
Published on: February 27, 2026
Utilization of coagulation assays in clinical therapeutics
Goldie L Peters1, P Benjamin Erwin, Matthew K Pitlick
1John Cochran Division, Ambulatory Care Clinical Pharmacist, VA St. Louis Healthcare System, St. Louis College of Pharmacy, St. Louis, Missouri.
Abstract:
With the emergence of new anticoagulants, clinicians need a thorough understanding of coagulation assays. Various laboratory assays exist to measure the effectiveness of anticoagulants. Coagulation assays are the primary method for measuring the effectiveness of anticoagulants; therefore, a comprehensive understanding of the various assays is critical to interpret the results appropriately. Coagulation test results can be affected by multiple factors including diseases, drugs, and genetic variations. This article reviews the indications, limitations, and interpretation of coagulation assays.
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