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A method for synthesis of homoallylic bromide

Wenke Qi1, Peipei Wang, Liyuan Fan

  • 1Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Dushu Lake Campus, Soochow University, Suzhou 215123, People's Republic of China.

The Journal of Organic Chemistry
|May 22, 2013
PubMed
Summary

Cyclopropyl Grignard reagents can be converted into valuable homoallylic bromides using carbonyl compounds and diethyl phosphite. This efficient one-pot reaction proceeds under mild conditions, offering moderate to good yields for synthetic chemists.

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