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Depression and its associated factors in pediatric chronic kidney disease

Amy J Kogon1, Ann Vander Stoep, Noel S Weiss

  • 1Division of Pediatric Nephrology, Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA. ak483@columbia.edu

Pediatric Nephrology (Berlin, Germany)
|May 24, 2013
PubMed

Insights

Depression is common in children with chronic kidney disease (CKD), especially in those with long-standing disease or at stage III CKD. This study identified associated clinical and demographic factors in pediatric CKD patients.

Area of Science:

  • Pediatric Nephrology
  • Child and Adolescent Psychiatry
  • Clinical Psychology

Background:

  • Limited research exists on depression prevalence in pediatric chronic kidney disease (CKD).
  • No studies have identified clinical or demographic factors associated with depression in this population.

Purpose of the Study:

  • To determine the occurrence of depression in pediatric patients with CKD.
  • To identify associated clinical and demographic factors.

Main Methods:

  • Cross-sectional study of 44 patients aged 9-18 years with CKD stages III-V.
  • Child Depression Inventory-2 (CDI-2) administered to assess depression.
  • Relative risks (RR) and 95% confidence intervals (CI) calculated for associations.

Main Results:

  • 13 out of 44 patients (30%) met depression criteria.
  • Depression was more prevalent in older adolescents (≥13 years) compared to younger children (<13 years).
  • A trend suggested lower depression risk with shorter CKD duration and later CKD stages (IV, V) versus stage III.

Conclusions:

  • Depression is a significant issue in children with CKD.
  • Longstanding renal disease and stage III CKD are associated with higher depression risk.
  • Further research is needed to explore these associations and inform interventions.
Abstract

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