[Water-salt metabolism in space flights]

The article centres on the water-salt metabolism properties in space flights of varying duration. To assess the water and mineral turnover, renal function and their hormonal regulation in flight, a series of experiments was carried out with participation of Russian and international cosmonauts. These experiments and ground model investigations shed light on the mechanisms of osmotic and volumetric regulation in microgravity and guided the development of countermeasures and methods for correcting the negative shifts as a result of body adaptation to the novel environment.