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Organization of the Nervous System

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The nervous system is one of the most complex systems in our body. It is organized into two main divisions: the central nervous system (CNS) and the peripheral nervous system (PNS).
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Extending...

Functional Divisions of the Nervous System

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The nervous system, responsible for sensing, integrating, and responding to various stimuli, is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The PNS has two functional divisions: the sensory or afferent division and the motor or efferent division.
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Functions of the Nervous System

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The human nervous system is divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and spinal cord, while the PNS contains nerve cells, clusters of nerve cells, and the sensory receptors that are outside the CNS. The PNS has two types of nerve cells: sensory (afferent) and motor (efferent). Sensory cells send signals to the CNS from receptors, and motor cells carry signals from the CNS to organs, muscles, and...

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Related Experiment Video

Updated: May 11, 2026

Imaging Cleared Intact Biological Systems at a Cellular Level by 3DISCO

Imaging Cleared Intact Biological Systems at a Cellular Level by 3DISCO

Published on: July 7, 2014

CLARITY for mapping the nervous system.

Kwanghun Chung¹, Karl Deisseroth

¹Department of Bioengineering, Stanford University, Stanford, California, USA. khchung@mit.edu

|June 1, 2013

Summary

This summary is machine-generated.

New hydrogel structures can be built within biological tissue for advanced brain mapping. This technique enables lipid removal, creating a stable, fine-structure-preserving hybrid permeable to light and molecules.

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Last Updated: May 11, 2026

Imaging Cleared Intact Biological Systems at a Cellular Level by 3DISCO

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Published on: July 7, 2014

Revealing Neural Circuit Topography in Multi-Color

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Published on: November 14, 2011

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY

Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY

Published on: June 30, 2016

Area of Science:

Biotechnology
Neuroscience
Materials Science

Background:

Hydrogel-based structures offer potential for advanced brain-mapping techniques.
Current methods may face limitations in preserving tissue integrity during analysis.

Purpose of the Study:

To introduce a novel method for in-situ hydrogel construction within biological tissue.
To enable lipid removal without mechanical tissue disassembly for enhanced imaging and analysis.
To explore the integration of this technique with existing brain-mapping methodologies.

Main Methods:

In-situ formation of hydrogel-based structures within biological tissue.
Subsequent removal of lipids from the tissue-hydrogel hybrid.
Assessment of structural, molecular, and optical properties of the resulting hybrid.

Main Results:

A physically stable tissue-hydrogel hybrid was successfully created.
The process preserved fine tissue structure, proteins, and nucleic acids.
The hybrid demonstrated permeability to visible-spectrum photons and exogenous macromolecules.

Conclusions:

This approach offers a new avenue for brain-mapping studies by creating a stable, optically transparent, and molecularly preserved tissue-hydrogel hybrid.
Challenges and opportunities exist for integrating this method with complementary brain-mapping technologies.
Further research can optimize this technique for detailed neurobiological investigations.