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Updated: May 11, 2026

Digital Inline Holographic Microscopy (DIHM) of Weakly-scattering Subjects
Published on: February 8, 2014
Near-field ptychography: phase retrieval for inline holography using a structured illumination.
Marco Stockmar1, Peter Cloetens, Irene Zanette
1Department of Physics and Institute for Medical Engineering, Technische Universität München, 85748 Garching, Germany. marco.stockmar@ph.tum.de
This study introduces near-field ptychography for improved X-ray phase imaging. This method accurately retrieves sample and illumination functions, reducing artifacts and enhancing phase tomography robustness.
Area of Science:
- Phase-contrast imaging
- X-ray microscopy
- Diffraction imaging
Background:
- Inline holography encodes phase information using free-space propagation.
- Quantitative imaging in inline holography is challenging due to sample or propagation distance constraints.
Purpose of the Study:
- To present a novel method for simultaneously retrieving a sample's complex-valued transmission function and incident illumination function.
- To improve the robustness and reduce artifacts in propagation-based X-ray phase tomography.
Main Methods:
- Utilizing near-field diffraction patterns from laterally translated samples under structured illumination.
- Applying a reconstruction approach analogous to ptychography.
- Validating the method with hard X-ray synchrotron measurements and simulations.
Main Results:
- Successful simultaneous retrieval of sample transmission function and illumination function.
- Demonstrated reduction of reconstruction artifacts compared to traditional inline holography.
- Relaxation of constraints on sample scattering properties.
Conclusions:
- Near-field ptychography offers a more robust approach to X-ray phase tomography.
- The method effectively factors out wavefront imperfections, enhancing quantitative imaging.
- This technique is expected to improve the accuracy and applicability of phase-contrast X-ray imaging.
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